BackgroundIdentifying new biomarkers of major depressive disorder (MDD) would be of great significance for its early diagnosis and treatment.Herein, we constructed a diagnostic model of MDD using machine learning methods.MethodsThe GSE98793 and GSE19738 datasets were obtained from the Gene Expression Omnibus database, and the limma R package was us
Cancer immunotherapy has led to impressive advances in cancer treatment.Unfortunately, in a high percentage of patients is difficult to consistently restore immune responses to eradicate established tumors.It is well accepted that adaptive immune cells, such as B lymphocytes, CD4+ helper T lymphocytes, and CD8+ cytotoxic T-lymphocytes (CTLs), are t
Abstract Background Transposable element-embedded regulatory sequences (TEeRS) and their KRAB-containing zinc finger protein (KZFP) controllers are increasingly recognized as modulators of gene expression.We aim to characterize the contribution of this system to gene regulation in early human development and germ cells.Results Here, after studying
Suspended monorail trains represent an important component of urban rail transit and this mode of transportation is regarded as promising for applications in China.This paper begins with an introductory interview of the development of suspended monorail trains and subsequently analyzes the technical schemes of the Optics Valley Photon suspended mon
Within the context of globalization, social workers need to ensure that international-level professional knowledge and practice do not lead to the oppression of the local people that the profession seeks to serve.One of the challenges for social workers is how to negotiate the sometimes-competing definitions and demands of local and cultural norms